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 Automation chemist for quant LC/MS/MS bioanalysis
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Mohammed Jemal
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1 Posts
Posted - 11/21/2002 :  12:07:34  Show Profile  Reply with Quote
The successful candidate will be the automation leader in the Department of Bioanalytical Sciences charged with quantitative bioanalysis for drugs and metabolites in all phases of drug development, spanning from early development through phase IV. The candidate will be responsible for identifying viable biological sample extraction automation approaches for LC/MS/MS bioanalysis and other bioanalytical techniques, standardizing extraction procedures and materials for use throughout the Department. The individual is expected to intimately keep abreast of new developments in the automation and continuously introduce new viable techniques and equipment. The candidate will be the lead person to introduce bioanalysts to new automation technology and procedures, helping with its successful implementation throughout the department. The candidate will work towards the achievement of total automation for methods development and sample analyses. This is expected to result in development of more rugged bioanalytical methods and use of large batches for sample analysis, thereby significantly enhancing the quality and throughput of sample analysis in Bioanalytical Sciences.

A proven record is required for the achievement and interest in sample extraction, separations science and automation for quantitative LC/MS/MS bioanalysis. A strong record of publications in this area is a definite plus. Should be a research-oriented person that is highly interested in following/monitoring emerging new technologies/ideas and then picking the viable ones and implementing them. Sound knowledge of 96-well based automation techniques using liquid handling robots (Packard, Tecan, etc.). A knowledge of electronics and programming languages related to the automation tools is desired. Other required skills include sound knowledge in the chemistries of extraction techniques and analyte stability related issues, and working knowledge in HPLC and API mass spectrometry. Interpersonal skills required for working with diverse individuals/groups in order to lead the successful implementation of the new technologies/ideas.

   
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