Qualifications and background
* Experienced in methods and technology development for Drug Discovery, Formulation, and QC labs.
* Expert in interfacing and programming laboratory automation and analytical systems.
* Strong analytical abilities.
* Experienced in providing analytical and automation support for Drug
Discovery, Synthetic, MAP, Formulations, and QC chemists.
* Experienced in cGMP / FDA work environment.
* Creative problem solver with a high degree of mechanical, computer, and chemical expertise.

Achievements
Implemented sample prep routines on common automation platforms such as Zymark, Tecan, Gilson, Packard, CRS, Hudson, and Cavro.
Invented and implemented new technologies for semi-prep chromatography, producing dried fractions in less than 1 hour.
Investigated and resolved problems in production and QC environments using techniques including MS, XRF, and chemical imaging microscopy.
Managed multi-disciplinary projects to meet deadlines and ensure successful completion.
Designed and built a number of systems to aid chemists and improve lab efficiency. These included automated resin processing systems for solid phase chemistry, new extraction and isolation techniques, and barcode tracking procedures for lab reagents and supplies.
Invented new liquid detection system to validate robotic liquid transfers
Developed containerized chemistry concept to improve resin handling for solid phase chemistry through automatic tracking of reactions and minimizing reagent use. This included an automated reaction processor to manipulate reagents and wash solutions.
Developed automation systems using Tecan, Zymark, and Nimbl equipment to perform synthesis for chemical library generation.
Developed analytical methods for raw materials, solid dose, and suspensions including NIR, Dissolution (USP apparatus II and IV), Particle Size, Assay, and Content Uniformity testing.
Integrated instruments (such as Agilent and Waters HPLC's) to automation and data systems to improve lab efficiency.
Connected automation systems to the Internet for remote access and control
Participated in new hire process for staffing of development lab.

Experience
Andrx Pharmaceuticals (FL) 2004
Supervisor, Automation and Robotics Group
Supervised group of 5 permanent and 2 temporary employees involved in new implementations of laboratory automation and LIMS
Currently undergoing a reorganization and realignment.

Tunnell Consulting (PA) 2003
Consultant - Analytical Chemistry
Provide analytical support for a formulations group.
Re-analyze and report on data in relation to an FDA filing
This was a series of temporary positions until a permanent position was found.

Yamanouchi Pharma. Tech. (OK) 2002
Scientist - Methods Development Laboratory
Provided analytical and technical support for Formulations laboratory
Performed analytical methods development for solid dosage testing in QC lab.
Performed method and equipment validation in QC/ cGMP / FDA environment.
Managed in-house projects involving multiple departments and projects involving external vendors.
The site was downsized and eventually sold.

Coelacanth Corp. (NJ) 2000
Lead Systems Integration Engineer
Developed automation systems to perform synthesis of chemical libraries
Supported in-house programs written by other developers
Provide instrument and computer support for analytical and production chemists
The company was bought by Lexicon Genetics and consolidated with existing operations.

Vertex Pharmaceuticals Inc. (MA) 1996
Automation Systems Integrator
Provided automation and analytical support for drug discovery group
Implemented new technologies for semi-prep chromatography, producing dried fractions in less than 1 hour.
Designed and built a number of systems to aid chemists and improve lab efficiency. These included automated resin processing systems for solid phase chemistry, new extraction and isolation techniques, and barcode tracking procedures for lab reagents and supplies.
Developed containerized chemistry concept to improve resin handling for solid phase chemistry through automatic tracking of reactions and minimizing reagent use. This included an automated reaction processor to manipulate reagents and wash solutions.
Managed 3rd party development projects to meet deadlines and ensure success
Moved to Coelacanth for the challenge of automating chemical syntheses.

American Cyanamid (NJ) 1995
Research Chemist
Implemented automated sample prep and analysis routines on Zymark robots until American Home Products bought the company and site was shut down.

Bristol-Myers Squibb (NJ) 1992
Research Chemist
Provided analytical and automation support for MAP group.
Invented new liquid detection system to validate robotic liquid transfers
Developed technology to improve efficiency of clinical trial analysis.
Moved to American Cyanamid for a diversity of challenges.

Education
Doctor of Chemistry University of Texas at Dallas
M.S. - Chemistry University of Texas at Dallas
B.S. - Chem. / Comp. Sci. Tarleton State University
(Cum Laude)

Training
IVT seminars on NIR Applications in PAT. 2005
National Seminars course on Project Planning, 2004
Skillpath seminars on budgeting and management, 2002
"Managing The Modern Analytical Lab" ALMA conf. 2002
Zymark AIS certification training
Beginning and Advanced Multi-Probe Programming (Packard dispenser)
Novell network administrator

LRIG Forum

Administrator: Andy Zaayenga, [email protected]

?2002 Laboratory Robotics Interest Group