Trident Synthesizer:Air-sensitive reagents

Reaction Reagent

Alkylation KHMDS, LiHMDS

Hydroboration 9-BBN

Reductive Amination NaBH4

Reduction L-Selectride

Pd Cross-coupling Pd(0)Ln

Pd Aryl Amination Pd(0)Ln

1,3-Dipolar Addition TiF4

Mitsunobu DEAD, PPh3

Nucleophilic Addition RMgX, RLi

Couplings PyBOP

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