Multistep Synthesis

• Key Reagents:

  • SnCl2 - 2 H2O
  • Polymer-bound Carbodiimide

• Reaction Control:

  • Elevated reaction temperature (SNAr step)
  • Equivalent stoichiometry

• Purification

  • Liquid-Liquid Extraction
  • Solid Phase Extraction (SPE)

1-PhenylBenzimidazoles

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