Picoliter to femtoliter liquid array micro-dispensers

From: philippe.luginbuhl@imt.unine.ch
Date: 09 Sep 1999

Comments

We have developped a DNA-injector for mass spectrometry which allows us to manipulate liquids in the femtoliter range (www-samlab.unine.ch). We are currently developping a micro-device (based on the silicon technology) for liquid handling which enables to dipense arrays of small droplets (0.01 to 0.5 pl) over a test-plate. The array consist of more then 96 injectors connected to a small liquid reservoir (1 micro-liter). Is there any potential interests of using this technology for automated liquid handlers in the femtoliter-picoliter range ? (e.g. liquid thin film deposition for test applications, DNA diagnostics, biochemical assays,...)

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